diff --git a/config.go b/config.go
new file mode 100644
index 0000000..572fc94
--- /dev/null
+++ b/config.go
@@ -0,0 +1,29 @@
+package sqlite3
+
+import "github.com/ncruces/go-sqlite3/internal/util"
+
+// Config makes configuration changes to a database connection.
+// Only bool configuratiton options are supported.
+// Called with no arg reads the current configuration value,
+// called with one arg sets and returns the new value.
+//
+// https://sqlite.org/c3ref/db_config.html
+func (c *Conn) Config(op DBConfig, arg ...bool) (bool, error) {
+	defer c.arena.mark()()
+	argsPtr := c.arena.new(2 * ptrlen)
+
+	var flag int
+	switch {
+	case len(arg) == 0:
+		flag = -1
+	case arg[0]:
+		flag = 1
+	}
+
+	util.WriteUint32(c.mod, argsPtr+0*ptrlen, uint32(flag))
+	util.WriteUint32(c.mod, argsPtr+1*ptrlen, argsPtr)
+
+	r := c.call("sqlite3_db_config", uint64(c.handle),
+		uint64(op), uint64(argsPtr))
+	return util.ReadUint32(c.mod, argsPtr) != 0, c.error(r)
+}
diff --git a/const.go b/const.go
index e10430e..49fda64 100644
--- a/const.go
+++ b/const.go
@@ -200,6 +200,34 @@ const (
 	STMTSTATUS_MEMUSED       StmtStatus = 99
 )
 
+// DBConfig are the available database connection configuration options.
+//
+// https://sqlite.org/c3ref/c_dbconfig_defensive.html
+type DBConfig uint32
+
+const (
+	// DBCONFIG_MAINDBNAME         DBConfig = 1000
+	// DBCONFIG_LOOKASIDE          DBConfig = 1001
+	DBCONFIG_ENABLE_FKEY           DBConfig = 1002
+	DBCONFIG_ENABLE_TRIGGER        DBConfig = 1003
+	DBCONFIG_ENABLE_FTS3_TOKENIZER DBConfig = 1004
+	DBCONFIG_ENABLE_LOAD_EXTENSION DBConfig = 1005
+	DBCONFIG_NO_CKPT_ON_CLOSE      DBConfig = 1006
+	DBCONFIG_ENABLE_QPSG           DBConfig = 1007
+	DBCONFIG_TRIGGER_EQP           DBConfig = 1008
+	DBCONFIG_RESET_DATABASE        DBConfig = 1009
+	DBCONFIG_DEFENSIVE             DBConfig = 1010
+	DBCONFIG_WRITABLE_SCHEMA       DBConfig = 1011
+	DBCONFIG_LEGACY_ALTER_TABLE    DBConfig = 1012
+	DBCONFIG_DQS_DML               DBConfig = 1013
+	DBCONFIG_DQS_DDL               DBConfig = 1014
+	DBCONFIG_ENABLE_VIEW           DBConfig = 1015
+	DBCONFIG_LEGACY_FILE_FORMAT    DBConfig = 1016
+	DBCONFIG_TRUSTED_SCHEMA        DBConfig = 1017
+	DBCONFIG_STMT_SCANSTATUS       DBConfig = 1018
+	DBCONFIG_REVERSE_SCANORDER     DBConfig = 1019
+)
+
 // Datatype is a fundamental datatype of SQLite.
 //
 // https://sqlite.org/c3ref/c_blob.html
diff --git a/embed/exports.txt b/embed/exports.txt
index 0fefb37..8017168 100644
--- a/embed/exports.txt
+++ b/embed/exports.txt
@@ -44,6 +44,7 @@ sqlite3_create_collation_go
 sqlite3_create_function_go
 sqlite3_create_module_go
 sqlite3_create_window_function_go
+sqlite3_db_config
 sqlite3_declare_vtab
 sqlite3_errcode
 sqlite3_errmsg
diff --git a/embed/sqlite3.wasm b/embed/sqlite3.wasm
index 1d2b2f7..b5dca1f 100755
Binary files a/embed/sqlite3.wasm and b/embed/sqlite3.wasm differ
diff --git a/tests/conn_test.go b/tests/conn_test.go
index cece594..8cf037b 100644
--- a/tests/conn_test.go
+++ b/tests/conn_test.go
@@ -289,3 +289,53 @@ func TestConn_Prepare_invalid(t *testing.T) {
 		t.Error("got message:", got)
 	}
 }
+
+func TestConn_Config(t *testing.T) {
+	t.Parallel()
+
+	db, err := sqlite3.Open(":memory:")
+	if err != nil {
+		t.Fatal(err)
+	}
+	defer db.Close()
+
+	o, err := db.Config(sqlite3.DBCONFIG_DEFENSIVE)
+	if err != nil {
+		t.Fatal(err)
+	}
+	if o != false {
+		t.Error("want false")
+	}
+
+	o, err = db.Config(sqlite3.DBCONFIG_DEFENSIVE, true)
+	if err != nil {
+		t.Fatal(err)
+	}
+	if o != true {
+		t.Error("want true")
+	}
+
+	o, err = db.Config(sqlite3.DBCONFIG_DEFENSIVE)
+	if err != nil {
+		t.Fatal(err)
+	}
+	if o != true {
+		t.Error("want true")
+	}
+
+	o, err = db.Config(sqlite3.DBCONFIG_DEFENSIVE, false)
+	if err != nil {
+		t.Fatal(err)
+	}
+	if o != false {
+		t.Error("want false")
+	}
+
+	o, err = db.Config(sqlite3.DBCONFIG_DEFENSIVE)
+	if err != nil {
+		t.Fatal(err)
+	}
+	if o != false {
+		t.Error("want false")
+	}
+}